Feb. 21, 2019

WHO experts on the Ebola vaccine.

Following a series of consultations and review of the evidence, the Strategic Advisory Group of Experts (SAGE) on Immunization, an independent advisory group convened by WHO, has provided updated recommendations on the use of Ebola vaccine.

The SAGE conclusions and recommendations can be summarized as follows:
Ring vaccination (vaccination of contacts and contacts of contacts) and geographic targeted vaccination continue to be the recommended strategies for Ebola vaccination with rVSV-ZEBOV-GP vaccine.
Consideration should be given to assessing one or more of the three other new Ebola vaccines (experimental or licensed but currently without data on efficacy) in areas neighboring the affected areas, and pregnant and breastfeeding women should be included in these trials.
In line with the committee’s assessment of October 2018, SAGE welcomes the DRC Ethics committee’s recommendation to authorize the use of rVSV-ZEBOV-GP vaccine in pregnant women in outbreak affected areas.
Immunization, Vaccines and Biologicals policy recommendations: https://www.who.int/immunization/policy/en/
SAGE Interim Recommendations on Vaccination against Ebola Virus Disease (EVD): https://www.who.int/immunization/interim_ebola_recommendations_feb_2019.pdf?ua=1